Howie Mandel is a celebrated comedian, television host, and actor, renowned for his unique blend of humor and versatility across various entertainment platforms. Rising to fame as Dr. Wayne Fiscus on the acclaimed medical drama St. Elsewhere, Mandel later became a household name through his iconic role as the host of the hit game show Deal or No Deal. His sharp wit and engaging presence also made him a fan favorite as a long-time judge on America’s Got Talent. Beyond his on-screen success, Mandel is known for his candid discussions about his struggles with obsessive-compulsive disorder, making him a vocal advocate for mental health awareness. His career, marked by resilience and a relentless pursuit of excellence, continues to inspire audiences both through his entertainment endeavors and his advocacy work.

0:00 - Howie discusses his initial skepticism about hosting Deal or No Deal.

0:39 - Facing show cancellations and contemplating leaving the entertainment industry.

0:58 - Howie explains his initial hesitation about game shows and the stigma attached.

4:00 - Howie recalls the unconventional pitch meeting that changed his mind.

6:30 - Howie’s wife encourages him to take the game show offer during a tough career moment.

8:45 - Howie discusses the human element of Deal or No Deal and how it shifted his approach.

10:16 - Howie reflects on the emotional impact of hosting his first episode.

11:33 - Howie describes the overwhelming success and unexpected audience reception.

12:00 - Howie talks about joining AGT and the challenges of being a judge.

14:00 - Howie shares the difficulty of critiquing performers in person.

17:45 - Reflecting on memorable performances and the emotional resonance of the show.

18:34 - Howie emphasizes the diversity and uniqueness of each act on AGT.

19:55 - Howie recounts his public struggle with OCD and the importance of speaking out.

24:34 - Howie’s perspective on success in comedy and his advice to aspiring comedians.

25:00 - Howie stresses the importance of persistence and taking action in any career.

29:23 - Howie discusses his philosophy of saying yes to opportunities and its impact.

30:00 - Howie views life as a game to be played, embracing challenges and opportunities.

34:01 - Howie explains the close relationship between comedy and tragedy.

37:26 - Howie’s belief in instinct over preparation in his career decisions.

43:04 - Howie discusses the role of luck and making your own opportunities.

44:35 - Howie emphasizes the importance of focusing on the current moment.

45:06 - Reflecting on the influence of Richard Pryor and authenticity in comedy.

49:18 - Howie on the importance of consistency and persistence in his personal and professional life.

52:32 - Howie compares life to a flowing river, advocating for staying engaged and curious.

53:09 - Howie’s involvement with Proto and his interest in new technologies.

1:01:44 - Howie shares what he would have done with a million dollars at 21.

1:03:42 - Howie answers rapid-fire questions on life lessons, regrets, and goals.